Urine samples for rabies RNA detection in the diagnosis of rabies in humans.

sessed. Resource constraints and financial pressures have become common in health care; if Saleh et al. [1] practice in settings where such constraints are absent, they are fortunate indeed. We conclude by agreeing with Hanssen et al. [2] that the use of modeling is not a substitute for well-designed randomized, controlled trials. These have been rare in the field of orthopedic infectious diseases but are badly needed. Until data from such trials become more widely available, we hope that our model will serve as an aid to decision making for clinicians involved in the management of these challenging infections.